SkinSeg is simple tool used for skin lesion segmentation. This little program was developed by Intelligent Systems laboratory students: L. Xu, M. Jackowski, A. Goshtasby, C. Yu, D. Roseman, S. Bines, A. Dhawan, A. Huntley. Their method is working similar as in my earlier experiment with matlab pigmented lesion boundary tracing algorithm. First image is converted to intensity image and then the lesion edges are detected.

malignant melanoma tracing boundary 

ant test results:

Malignant melanoma tracing 

More informative description you can find here 

Program can be downloaded from here: http://www.cs.wright.edu/people/faculty/agoshtas/skinseg.zip 

This version of the Skin Cancer Segmentation program (skinseg) runs on the Windows 95/NT platforms. Make sure all files reside in the same directory after extraction. No setup program is required to install skinseg on your machine. To run, execute the program skinseg.exe.